COVID-19 in patients with familial Mediterranean fever treated with colchicine: case based review.
Kemal NasNuran EryilmazMehmet Faruk GeyikAyfer AltaşPublished in: Rheumatology international (2021)
Coronavirus disease 2019 (COVID-19) refers to the clinical picture of an important and severe infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Considering the current knowledge on the pathophysiology and clinical manifestations of COVID-19, it is safe to state that both COVID-19 and inflammatory rheumatic disorders cause a cytokine storm and merit treatment with anti-rheumatic drugs. Three patients, who were on regular follow-up due to the diagnosis of familial Mediterranean fever (FMF), contracted COVID-19 infection; and their pre-clinical and post-clinical data as well as laboratory, prognosis and treatment data were investigated. Effects of colchicine in FMF patients who contracted COVID-19 infection were presented in this study. All the cases recovered from COVID-19 without complications. The present study suggests that colchicine can positively affect the prognosis of COVID-19 in FMF patients; therefore, experience of rheumatologists in the use of anti-inflammatory drugs can be highly instrumental in management of COVID-19 patients.
Keyphrases
- sars cov
- coronavirus disease
- respiratory syndrome coronavirus
- end stage renal disease
- healthcare
- early onset
- newly diagnosed
- electronic health record
- chronic kidney disease
- big data
- infectious diseases
- oxidative stress
- mass spectrometry
- ejection fraction
- prognostic factors
- artificial intelligence
- combination therapy
- single molecule