Mesenchymal Stem Cells Successfully Deliver Oncolytic Virotherapy to Diffuse Intrinsic Pontine Glioma.
Michael I ChastkofskyKatarzyna C PituchHiroaki KatagiMarkella ZannikouLiliana IlutTing XiaoYu HanAdam M SonabendDavid T CurielErin R BonnerJavad NazarianCraig M HorbinskiC David JamesAmanda Muhs SaratsisRintaro HashizumeMaciej S LesniakIrina V BalyasnikovaPublished in: Clinical cancer research : an official journal of the American Association for Cancer Research (2020)
Our study supports OV, CRAd.S.pK7, encapsulated within MSCs as a therapeutic strategy that merits further investigation and potential translation for DIPG treatment.