PARP inhibitor therapy in patients with IDH1 mutated cholangiocarcinoma.
Arathi MohanElit QuingalahuaValerie GunchickSimi PaulChandan Kumar-SinhaOxana CryslerMark M ZalupskiVaibhav SahaiPublished in: The oncologist (2024)
This is the first case series to describe PARPi treatment in IDH1 mutated iCCA. Results underscore the limitation of PARPi monotherapy, potentially support combined PARPi therapies, and highlight a need for effective treatment options for patients with IDH1 mutated iCCA.