Decellularized nucleus pulposus matrix/chitosan hybrid hydrogel combined with nucleus pulposus stem cells and GDF5-loaded microspheres for intervertebral disc degeneration prevention.

Tao MaChen LiuQuanlai ZhaoYu ZhangLiang Xiao

Published in: Molecular medicine (Cambridge, Mass.) (2024)

GDF5-loaded microspheres combined with DNPM/chitosan composite hydrogels can effectively promote the differentiation of NPSCs into nucleus pulposus-like cells and effectively preventIDD.

Keyphrases

drug delivery
wound healing
stem cells
cancer therapy
hyaluronic acid
drug release
tissue engineering
extracellular matrix
molecularly imprinted
cell therapy
mass spectrometry