Phytochemical profiling, antioxidant, cytotoxic, and anti-inflammatory activities of Plectranthus rugosus extract and fractions: in vitro, in vivo, and in silico approaches.

Reyaz Hassan MirRoohi Mohi-Ud-DinLamya Ahmed Al-KeridisBilal AhmadNawaf AlshammariMitesh PatelMohd AdnanMubashir Hussain Masoodi

Published in: Inflammopharmacology (2024)

The pro-inflammatory cytokines are inhibited by P. rugosus extracts, as well as an isolated compound oleanolic acid without compromising cell viability.

Keyphrases

anti inflammatory
molecular docking
single cell
oxidative stress
molecular dynamics simulations