Association Between Insulin Resistance and Cardiovascular Disease Risk Varies According to Glucose Tolerance Status: A Nationwide Prospective Cohort Study.
Tian-Ge WangMian LiTian-Shu ZengRuying HuYu XuYanan HouZhiyun ZhaoYuhong ChenShuangyuan WangHong LinXue-Feng YuGang ChenQing SuYi-Ming MuMingxing XieXulei TangLi YanGui-Jun QinQin WanZhengnan GaoGuixia WangFeixia ShenZuojie LuoYingfen QinLi ChenYanan HuoQiang LiZhen YeYinfei ZhangChao LiuYoumin WangShengli WuYang TaoHuacong DengJiajun ZhaoLi-Xin ShiYanqiu WangYu-Fang BiWei-Qing WangJie-Li LuPublished in: Diabetes care (2022)
Glucose intolerance status exacerbated the association between insulin resistance and CVD risk. Compared with adults with normal glucose tolerance, adults with prediabetes who were both insulin resistant and obese exhibited higher risks of CVD, while in adults with diabetes, the CVD risk related to insulin resistance remained, regardless of obesity.