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Temporal Stability of Heavy Drinking Days and Drinking Reductions Among Heavy Drinkers in the COMBINE Study.

Katie A WitkiewitzAdam D WilsonMatthew R PearsonKevin A HallgrenDaniel E FalkRaye Z LittenHenry R KranzlerKarl F MannDeborah S HasinStephanie S O'MalleyRaymond K Anton
Published in: Alcoholism, clinical and experimental research (2017)
The results show stability of no heavy drinking as an outcome within the first 4 months of treatment and that the >3/>4 drink cutoff may mask substantial reductions in alcohol consumption among some patients. Future studies should explore the clinical utility of reduction end points.
Keyphrases
  • alcohol consumption
  • end stage renal disease
  • ejection fraction
  • newly diagnosed
  • chronic kidney disease
  • patient reported outcomes
  • patient reported
  • case control
  • combination therapy