Clonal Hematopoiesis as a Molecular Risk Factor for Doxorubicin-Induced Cardiotoxicity: A Proof-of-Concept Study.

Jamila Mammadova Christelle M Colin-Leitzinger Diep Nguyen Rahul Mhaskar Shridar GanesanYi-Han TangMingxiang TengRoohi Ismail-Khan Nancy Gillis

Published in: JCO precision oncology (2023)

This study provides preliminary evidence for CH as a predictive risk factor for DIC, which, with further investigation, could serve as an important precision medicine biomarker for the large number of patients with cancer who have CH.

Keyphrases

room temperature
high glucose
drug delivery
diabetic rats
cancer therapy
oxidative stress