Regular football training down-regulates miR-1303 muscle expression in veterans.
A ManciniD VitucciF M OrlandellaA TerraccianoR M MarinielloE ImperliniE GrazioliS OrrùP KrustrupG SalvatorePasqualina BuonoPublished in: European journal of applied physiology (2021)
This is the first report, to our knowledge, describing miR-1303 regulation in skeletal muscle by football training and the identification of a target protein, BAG-2, involved in the autophagy pathway. This result contributes to the enlargement of knowledge on the molecular mechanisms linking football training, autophagy and longevity.