Identification of a Notch transcriptomic signature for breast cancer.

Eike-Benjamin BrauneFelix GeistXiaojia TangKrishna KalariJudy BougheyLiewei WangRoberto A Leon-FerreAntonino B D'AssoroJames N IngleMatthew P GoetzJulian KreisKang WangTheodoros FoukakisAnita SeshireDirk WienkeUrban Lendahl

Published in: Breast cancer research : BCR (2024)

The 20-gene transcriptional signature will be a valuable tool to evaluate the response of future Notch-targeting therapies for breast cancer, to learn about potential effects on Notch signalling from conventional breast cancer therapies and to better stratify patients for therapy considerations.

Keyphrases

end stage renal disease
cell proliferation
ejection fraction
chronic kidney disease
newly diagnosed
gene expression
prognostic factors
transcription factor
peritoneal dialysis
oxidative stress
copy number
single cell
cancer therapy
dna methylation
patient reported outcomes
young adults