Cell-free DNA copy number variations predict efficacy of immune checkpoint inhibitor-based therapy in hepatobiliary cancers.

Xu YangYing HuKeyan YangDongxu WangJianzhen LinJunyu LongFucun XieJinzhu MaoJin BianMei GuanJie PanLi HuoKe HuXiaobo YangYilei MaoXinting SangJiao ZhangXi WangHenghui ZhangHaitao Zhao

Published in: Journal for immunotherapy of cancer (2022)

The CNVs in plasma cfDNA could predict the clinical outcome of the combination therapy of PD-1 inhibitor with lenvatinib and other ICI-based therapies in hepatobiliary cancers.

Keyphrases

copy number
combination therapy
mitochondrial dna
genome wide
gene expression
young adults
childhood cancer
cell therapy