Vegf-A mRNA transfection as a novel approach to improve mouse and human islet graft revascularisation.

Willem StaelsYannick VerdonckYves HeremansGunter LeuckxSofie De GroefCarlo HeirmanEelco de KoningConny GysemansKris ThielemansLuc BaeyensHarry HeimbergNico De Leu

Published in: Diabetologia (2018)

Vegf-A mRNA transfection before transplantation provides a promising and safe strategy to improve engraftment of islets and other cell-based implants.

Keyphrases

endothelial cells
vascular endothelial growth factor
cell therapy
single cell
binding protein
induced pluripotent stem cells
stem cells
soft tissue