Adapting an organ-on-chip device to study the effect of fetal sex and maternal race/ethnicity on preterm birth related intraamniotic inflammation leading to fetal neuroinflammation.

Lauren S RichardsonNkechinyere EmeziennaIrina BurdBrandie DePaoli TaylorMorgan R PeltierArum HanRamkumar Menon

Published in: American journal of reproductive immunology (New York, N.Y. : 1989) (2022)

This OOC model of fetal neuroinflammation has determined that race/ethnicity differences do exist for perinatal brain injury. The fetal sex of neonates was not a determining factor of susceptibility to intraamniotic inflammation leading to neuroinflammation.

Keyphrases

brain injury
preterm birth
cerebral ischemia
lipopolysaccharide induced
traumatic brain injury
subarachnoid hemorrhage
oxidative stress
low birth weight
lps induced
cognitive impairment
pregnant women
gestational age
birth weight
preterm infants
blood brain barrier
body mass index