Performance of a HER2 testing algorithm specific for p53-abnormal endometrial cancer.
Lisa VermijNaveena SinghAlicia Leon-CastilloNanda HorewegJan OostingJoseph CarlsonVincent SmitC Blake GilksTjalling BossePublished in: Histopathology (2021)
Our EC-specific HER2 IHC scoring method is reproducible. A screening strategy based on IHC scoring on all cases with subsequent DISH testing on IHC-2+/-3+ cases has perfect test accuracy for identifying HER2-positive EC.