Nutritionally Derived Metabolic Cues Typical of the Obese Microenvironment Increase Cholesterol Efflux Capacity of Adipose Tissue Macrophages.

Marcella E O'ReillySarina KajaniJessica C RalstonYvonne M LenighanHelen M RocheFiona C McGillicuddy

Published in: Molecular nutrition & food research (2018)

These novel findings demonstrate remarkable plasticity of macrophages to respond to their environment with specific modulation of ABCA1 depending on whether classical pro-inflammatory or metabolic cues predominate.

Keyphrases

adipose tissue
insulin resistance
stem cells
high fat diet
metabolic syndrome
type diabetes
weight loss
obese patients
bariatric surgery