Eukaryotic Initiation Factor 3C Can Affect the Proliferation and Invasion of Ovarian Cancer by Regulating the p53 Signalling Pathway.

Jingkaiwen ZhangHanlin YangFang WenQing LiHao LuoDan Zi

Published in: Recent patents on anti-cancer drug discovery (2024)

There is a correlation between overexpression of EIF3C in tumour tissues of ovarian cancer patients and this is associated with a poorer prognosis. By influencing the p53 signaling pathway, EIF3C facilitates the growth and infiltration of cells in ovarian cancer.

Keyphrases

signaling pathway
induced apoptosis
end stage renal disease
ejection fraction
chronic kidney disease
newly diagnosed
gene expression
prognostic factors
cell cycle arrest
pi k akt
oxidative stress
patient reported outcomes
cell death