Silicone dressing combined with topical oxygen therapy alleviates incontinence-associated dermatitis via NF-κB p65/STAT1 signaling pathway.

Guiyu An ChenYingxun ChenYan ZhangShufeng ZhengLouying ZhuMingxing Ding

Published in: Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) (2024)

These findings indicated that silicone dressing combined with topical oxygen therapy can alleviate IAD through promoting wound healing and inhibiting inflammation via NF-κB p65/STAT1 signaling pathway in a rat model, which provided a theoretical basis for the prevention and treatment of IAD in clinic.

Keyphrases

signaling pathway
wound healing
pi k akt
induced apoptosis
epithelial mesenchymal transition
oxidative stress
cell proliferation
primary care
lps induced
stem cells
mouse model
nuclear factor
immune response
atopic dermatitis