Correlation between Heparin Anti-Xa Activity and Thromboelastography in Adult Critically Ill COVID-19 Patients.

Mitchell S BuckleyGrace E BenantiBrian GilbertJordan MeckelAmy L Dzierba Robert MacLaren

Published in: Pharmacotherapy (2023)

A low correlation was found between the TEG R time and anti-Xa activity, while no relationship existed between TEG R time and aPTT during therapeutic UFH anticoagulation in critically ill COVID-19 patients. The role of TEG to routinely monitor and guide UFH anticoagulation dosing remains inconclusive. Further research is necessary to address the laboratory tests needed to help with decision-making on anticoagulation dosing in patients with severe COVID-19.

Keyphrases

venous thromboembolism
sars cov
atrial fibrillation
decision making
coronavirus disease
respiratory syndrome coronavirus
young adults