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Leukocyte Immunoglobulin-Like Receptor A3 (LILRA3): A Novel Marker for Lymphoma Development among Patients with Young Onset Sjogren's Syndrome.

Evangelia ArgyriouAdrianos NezosPetros RoussosVenetsanopoulou I AlikiMichael VoulgarelisKyriaki BokiAthanasios G TzioufasHaralampos M MoutsopoulosClio P Mavragani
Published in: Journal of clinical medicine (2021)
The functional LILRA3 gene variant increases susceptibility to SS-related lymphoma development in patients with a disease onset of <40 years old, implying that genetically determined deranged immune responses in younger SS individuals could underly their pronounced risk for lymphoma development.
Keyphrases
  • diffuse large b cell lymphoma
  • immune response
  • gene expression
  • genome wide
  • toll like receptor
  • peripheral blood
  • middle aged