Evidence for activation of nitenpyram by a mitochondrial cytochrome P450 in Drosophila melanogaster.

Thomas W R HarropShane DeneckeYing Ting YangJanice ChanPhillip J DabornTrent PerryPhilip Batterham

Published in: Pest management science (2018)

These results suggest that in vivo metabolism of nitenpyram by the mitochondrial P450 CYP12A5 results in the formation of a product with higher toxicity than the parent compound. © 2018 Society of Chemical Industry.

Keyphrases

drosophila melanogaster
oxidative stress