Power and sample size calculation for stepped-wedge designs with discrete outcomes.

Fan XiaJames P HughesEmily C VoldalPatrick J Heagerty

Published in: Trials (2021)

Our method requires minimal computational power. Therefore, the proposed procedure facilitates rapid dynamic updates of sample size calculations and can be used to explore a wide range of design options or assumptions.

Keyphrases

monte carlo
molecular dynamics
density functional theory
molecular dynamics simulations
minimally invasive
study protocol
clinical trial
loop mediated isothermal amplification
metabolic syndrome
adipose tissue
quantum dots
insulin resistance