Esophageal Manometry and Regional Transpulmonary Pressure in Lung Injury.

Takeshi YoshidaMarcelo B P AmatoDomenico Luca GriecoLu ChenCristhiano A S LimaRollin RoldanCaio C A MoraisSusimeire GomesEduardo L V CostaPaulo F G CardosoEmmanuel CharbonneyJean-Christophe M RichardLaurent BrochardBrian P Kavanagh

Published in: American journal of respiratory and critical care medicine (2019)

These data support the use of esophageal manometry in acute respiratory distress syndrome. Assuming correct calibration, expiratory Pl derived from Pes reflects Pl in dependent to middle lung, where atelectasis usually predominates; inspiratory Pl estimated from elastance ratio may indicate the highest level of lung stress in nondependent "baby" lung, where it is vulnerable to ventilator-induced lung injury.

Keyphrases

acute respiratory distress syndrome
mechanical ventilation
extracorporeal membrane oxygenation
high glucose
intensive care unit
big data
stress induced
low cost
oxidative stress