Genetic control of temperament traits across species: association of autism spectrum disorder risk genes with cattle temperament.

Roy CostillaKathryn E KemperEnda M ByrneLaercio R Porto-NetoRoberto CarvalheiroDeirdre C PurfieldJennifer L DoyleDonagh P BerryStephen S MooreNaomi R WrayBen J Hayes

Published in: Genetics, selection, evolution : GSE (2020)

Our analysis showed that genes identified in a meta-analysis of cattle temperament contribute to neuron development functions and are differentially expressed in human brain tissues. Furthermore, some ASD susceptibility genes are associated with cattle temperament. These findings provide evidence that genetic control of temperament might be shared between humans and cattle and highlight the potential for future analyses to leverage results between species.

Keyphrases

genome wide
autism spectrum disorder
dna methylation
bioinformatics analysis
genome wide identification
copy number
intellectual disability
attention deficit hyperactivity disorder
gene expression
transcription factor