Blood extracellular vesicles carrying synaptic function- and brain-related proteins as potential biomarkers for Alzheimer's disease.

Chen TianTessandra StewartZhen HongZhen GuoPatrick AroDavid SoltysCatherine PanElaine R PeskindCyrus P ZabetianLeslie M ShawDouglas GalaskoJoseph F QuinnMin ShiJing Zhangnull null

Published in: Alzheimer's & dementia : the journal of the Alzheimer's Association (2022)

This study demonstrated that robust and rapid analysis of individual neuron-derived synaptic function-related EVs in peripheral blood may serve as a helpful marker of synaptic dysfunction in AD and dementia.

Keyphrases

peripheral blood
prefrontal cortex
mild cognitive impairment
oxidative stress
cognitive impairment
brain injury