Mixed germ cell testicular cancer with left ventricular metastasis presenting with embolic stroke and small bowel tumor seeding.
Srinath SundararajanBeth BraunhutFrederick AhmannAmit AgarwalPublished in: Case reports in oncological medicine (2014)
Testicular germ cell tumors (GCTs) metastasize in a very predictable fashion involving the retroperitoneal nodes first followed by hematogenous spread to distant organs like lungs, liver, and brain. Metastasis to heart is an extremely rare entity for GCT and fewer than 20 cases have been reported in the literature so far. We have summarized here a unique case of nonseminomatous germ cell tumor (NSGCT) with intracardiac metastasis resulting in systemic macroembolization to liver, spleen, brain, bowel and musculoskeletal tissues. This led to multiple adverse sequelae including ischemic stroke and bowel perforation.
Keyphrases
- germ cell
- small bowel
- atrial fibrillation
- left ventricular
- resting state
- white matter
- heart failure
- cerebral ischemia
- systematic review
- functional connectivity
- gene expression
- papillary thyroid
- acute myocardial infarction
- lymph node
- left atrial appendage
- multiple sclerosis
- sentinel lymph node
- case report
- acute coronary syndrome
- emergency department
- hypertrophic cardiomyopathy
- coronary artery disease
- neoadjuvant chemotherapy