Initial Whole-Genome Sequencing of Plasma Cell Neoplasms in First Responders and Recovery Workers Exposed to the World Trade Center Attack of September 11, 2001.
Francesco MauraBenjamin T DiamondKylee H MaclachlanAndriy DerkachVenkata D YellapantulaEven Holth RustadMalin HultcrantzUrvi A ShahJessica HongHeather J LandauChristine A Iacobuzio-DonahueElli PapaemmanuilShani IrbyLaura CrowleyMichael CraneMayris P WebberDavid G GoldfarbRachel Zeig-OwensOrsi GiriczAmit VermaDavid J PrezantAhmet DoganYanming ZhangOla LandgrenPublished in: Clinical cancer research : an official journal of the American Association for Cancer Research (2021)
Although limitations in sample size preclude any definitive conclusions, our findings suggest that the observed increased incidence of plasma cell neoplasms in this population is due to complex and heterogeneous effects of the WTC exposure that may have initiated or contributed to progression of malignancy.