Genome-wide Polygenic Risk Scores Predict Risk of Glioma and Molecular Subtypes.

Taishi Nakase Geno A Guerra Quinn T Ostrom Tian Ge Beatrice MelinMargaret WrenschJohn K WienckeRobert B JenkinsJeanette E Eckel-Passownull nullMelissa L Bondy Stephen S Francis Linda Kachuri

Published in: medRxiv : the preprint server for health sciences (2024)

Our novel genome-wide PRS may improve the identification of high-risk individuals and help distinguish between prognostic glioma subtypes, increasing the potential clinical utility of germline genetics in glioma patient management.

Keyphrases

genome wide
dna methylation
copy number
case report
dna repair
climate change