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Do hemodynamics matter in the treatment of patients with submassive pulmonary emboli?

Morton J KernArnold H Seto
Published in: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions (2020)
The present article examines the right heart (RH) pressures of patients with submassive pulmonary embolism before and after catheter-directed thrombolysis (CDT). 40% of patients had a low cardiac output (CI ≤1.8 L/min/m2 ) despite normally preserved blood pressure. After thrombolysis, CI increased and pulmonary artery pressures decreased. Although routine RH pressure measurements may help in CDT management and possibly serve as a surrogate outcome measure, more comprehensive pulmonary embolism trials are needed to solidify the role of hemodynamics in this setting.
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