Pancreatic undifferentiated carcinoma with osteoclast-like giant cells curatively resected after pembrolizumab therapy for lung metastases: a case report.

Miku ObayashiYasushi ShibasakiToru KoakutsuYoshiro HayashiTsuyoshi ShojiKazuhisa HirayamaMasanori YamazakiYasuhiro TakayanagiHiroshi ShibataMasato NakamuraHirotoshi Maruo

Published in: BMC gastroenterology (2020)

Immune checkpoint inhibitors have limited therapeutic effects on primary lesions of pancreatic cancer, but they may exert antitumor effects on pulmonary metastases of UCOGC.

Keyphrases

induced apoptosis
cell cycle arrest
pulmonary hypertension
lymph node
advanced non small cell lung cancer
endoplasmic reticulum stress
signaling pathway
oxidative stress
bone loss
cell proliferation