A New Multi-Color FISH Assay for Brush Biopsy-Based Detection of Chromosomal Aneuploidy in Oral (Pre)Cancer in Patients with Fanconi Anemia.
Bruno Eduardo Silva de AraujoMona MarkgrafIsabela Karoline de Santana Almeida AraujoEunike VelleuerRalf DietrichNatalia PomjanskiMartin SchrammPublished in: Cancers (2022)
Multi-color FISH is a sufficient tool to detect chromosomal aneuploidy in oral (pre) malignant lesions of individuals with Fanconi anemia. However, some false positive results may hamper the application as an adjuvant method to oral brush biopsy-based cytology in an oral cancer surveillance program.