Integrative testis transcriptome analysis reveals differentially expressed miRNAs and their mRNA targets during early puberty in Atlantic salmon.
Kai Ove SkaftnesmoR B EdvardsenT FurmanekD CrespoE AnderssonL KleppeG L TarangerJ BogerdR W SchulzA WargeliusPublished in: BMC genomics (2017)
This study has - for the first time - linked testis maturation to specific miRNAs and their inversely correlated expressed targets in Atlantic salmon. The study indicates a broad functional conservation of already known miRNAs and associated pathways involved in the transition into puberty in vertebrates. The analysis also reveals miRNAs not previously associated with testis tissue or its maturation, which calls for further functional studies in the testis.
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