Correlation between a 10-color flow cytometric measurable residual disease (MRD) analysis and molecular MRD in adult B-acute lymphoblastic leukemia.

Jasmine SinghMalgorzata GorniakGeorge GrigoriadisDavid WestermanMichelle McBeanNicola VennTamara LawRosemary SuttonSue MorganShaun Fleming

Published in: Cytometry. Part B, Clinical cytometry (2021)

Our 10-color flow cytometric MRD assay provided adequate sensitivity and good correlation with molecular assays. This technique offers rapid and affordable testing in B-ALL patients, including cases where a suitable molecular assay cannot be developed or has reduced sensitivity.

Keyphrases

acute lymphoblastic leukemia
high throughput
end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
prognostic factors
peritoneal dialysis
acute myeloid leukemia
patient reported
single cell
quantum dots