Trajectories of depression symptom change during and following treatment in adolescents with unipolar major depression.
Sian Emma DaviesSharon A S NeufeldEleonore van SprangLizanne SchwerenRogier KeivitFonagy PBernadka DubickaRaphael KelvinNick MidgleyShirley ReynoldsMary TargetPaul WilkinsonAnne Laura van HarmelenIan Michael GoodyerPublished in: Journal of child psychology and psychiatry, and allied disciplines (2019)
A fast reduction in depressive symptoms in the first few weeks of treatment may not indicate a good prognosis. Halted improvement is only seen after 18 weeks of treatment. Longitudinal modelling may improve the precision of revealing differential responses to treatment. Improvement in depressive symptoms may be somewhat better in the year after treatment than previously considered.