Undetectable PSA predicts outcome after salvage radiotherapy for biochemical recurrence following radical prostatectomy.

Sophia ScharlLuca GartnerDirk Heinz Gerhard BöhmerAlessandra SiegmannReinhard ThammManuel KrafcsikBenjamin MayerDaniel ZipsChristian RufThomas Wiegel

Published in: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology (2024)

PSA < 0.1 ng/mL following SRT without ADT is a significant predictor of BPFS and MFS. The results suggest that it might be feasible to withhold ADT in selected patients if they have undetectable PSA after SRT. Prospective studies are warranted to confirm these findings.

Keyphrases

radical prostatectomy
prostate cancer
end stage renal disease
newly diagnosed
chronic kidney disease
ejection fraction
radiation therapy
prognostic factors
peritoneal dialysis
radiation induced
locally advanced
patient reported