The effects of thymoquinone on pancreatic cancer and immune cells.

Celal Alandağ Derya Dilek Kançağı Gözde Sır Karakuş Didem Çakirsoy Ercüment Ovalı Elanur Karaman Elif Yüce Feyyaz Özdemir

Published in: Revista da Associacao Medica Brasileira (1992) (2022)

Since the cytotoxic concentration of thymoquinone on pancreatic cancer cell culture and mesenchymal stem cells is the same, it is not appropriate to use thymoquinone to achieve cytotoxicity in pancreatic cancer. However, since thymoquinone provides proliferation in peripheral blood mononuclear cell at a noncytotoxic dose, it may have an immune activator effect. Therefore, in vivo studies are needed to investigate the effect of thymoquinone on the immune system.

Keyphrases

peripheral blood
mesenchymal stem cells
single cell
signaling pathway
bone marrow
stem cells
nuclear factor