Anti-CD74 IgA antibodies show diagnostic potential for axial spondyloarthritis but are not associated with microscopic gut inflammation.

Ann-Sophie De CraemerTorsten WitteTriana Lobaton OrtegaAnne HoorensMartine De VosClaude CuvelierSebastiaan J VastertXenofon BaraliakosFilip Van den BoschDirk Elewaut

Published in: Rheumatology (Oxford, England) (2022)

Serum anti-CD74 IgA is a potentially useful diagnostic biomarker for axSpA. However, antibody levels do not correlate with any phenotypical feature, including microscopic gut inflammation, suggesting this to be a disease-specific rather than an inflammatory marker.

Keyphrases

oxidative stress
machine learning
nk cells
ankylosing spondylitis
deep learning
rheumatoid arthritis
human health
climate change