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Imaging of Cancer γ-Secretase Activity Using an Inhibitor-Based PET Probe.

Pengju NieTeja KalidindiVeronica L NagleXianzhong WuThomas LiGeorge P LiaoGeorgia FrostKelly E HenryBlesida PunzalanLukas Michael CarterJason S LewisNaga Vara Kishore PillarsettyYue-Ming Li
Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2021)
[124I]-PN67 is a novel PET imaging agent that enables assessment of γ-secretase activity and target engagement of clinical GSIs.
Keyphrases
  • pet imaging
  • positron emission tomography
  • papillary thyroid
  • high resolution
  • social media
  • pet ct
  • squamous cell
  • living cells
  • quantum dots
  • young adults
  • photodynamic therapy
  • lymph node metastasis
  • childhood cancer