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Real-world data on the prevalence of BRCA1/2 and HRR gene mutations in patients with primary and metastatic castration resistant prostate cancer.

Moritz HommerdingOliver HommerdingMarit BernhardtTobias KreftChristine SandersVerena TischlerPatrick BasittaNatalie PelusiAnna-Lena WulfCarsten-Henning OhlmannJörg EllingerManuel RitterGlen Kristiansen
Published in: World journal of urology (2024)
This study offers valuable real-world insights into the landscape of BRCA1/2 and HRR gene mutations and the practical clinical management of HRR gene testing in prostate cancer, contributing to a better understanding of patient eligibility for PARPi treatment.
Keyphrases
  • prostate cancer
  • squamous cell carcinoma
  • radical prostatectomy
  • small cell lung cancer
  • risk factors
  • case report
  • copy number
  • genome wide
  • breast cancer risk
  • single cell
  • dna methylation
  • combination therapy