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Host genetic polymorphisms and serological response against malaria in a selected population in Sri Lanka.

Rajika L DewasurendraAnna JeffreysSharmini A GunawardenaNaduviladath V ChandrasekharanKirk RockettDominic KwiatkowskiNadira D Karunaweera
Published in: Malaria journal (2018)
The study suggests that several SNPs in the human genome that exist in Sri Lankan populations are significantly associated with anti-malarial antibodies, either with generation and/or maintenance of antibodies for longer periods, which can be due to either individual polymorphisms or most probably a combined effect of the markers.
Keyphrases
  • endothelial cells
  • plasmodium falciparum
  • genome wide
  • induced pluripotent stem cells
  • dna methylation