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Radiosensitisation of Hepatocellular Carcinoma Cells by Vandetanib.

Sami A ZnatiRebecca CarterMarcos VasquezAdam WesthorpeHassan ShahbakhtiJessica PrincePetra VlckovaChiara De VellisZainab A BascalMarilena LoizidouRicky A Sharma
Published in: Cancers (2020)
In 2D and 3D studies in vitro and in a syngeneic model in vivo, the combination of vandetanib plus radiotherapy was more efficacious than either treatment alone. This new combination therapy for HCC merits evaluation in clinical trials.
Keyphrases
  • clinical trial
  • locally advanced
  • radiation induced
  • squamous cell carcinoma
  • open label
  • study protocol
  • double blind
  • placebo controlled