18F-florbetapir PET as a marker of myelin integrity across the Alzheimer's disease spectrum.
Alexis MoscosoJesús Silva-RodríguezJose Manuel AldreyJulia CortésJuan Manuel Pías-PeleteiroÁlvaro RuibalPablo Aguiarnull nullPublished in: European journal of nuclear medicine and molecular imaging (2021)
These results support the hypothesis that FBP retention in the WM is myelin-related. Demyelination levels progressed across the AD continuum and were associated with clinical progression at early stages, suggesting that this pathologic process might be a relevant degenerative feature in the disease course.