The prognostic value of extranodal extension in human papillomavirus-associated oropharyngeal squamous cell carcinoma.
Yi AnHenry S ParkJacqueline R KellyJohn M StahlWendell G YarbroughBarbara A BurtnessJoseph N ContessaRoy H DeckerMatthew KoshyZain A HusainPublished in: Cancer (2017)
ENE is associated with inferior OS in patients with HPV-positive OPSCC. However, OS was not better with adjuvant chemoradiotherapy compared with radiotherapy alone in ENE-positive patients. The current findings support the need for prospective studies of adjuvant chemoradiation in HPV-positive patients with ENE. Cancer 2017;123:2762-72. © 2017 American Cancer Society.
Keyphrases
- locally advanced
- squamous cell carcinoma
- early stage
- papillary thyroid
- rectal cancer
- end stage renal disease
- squamous cell
- high grade
- lymph node metastasis
- ejection fraction
- newly diagnosed
- chronic kidney disease
- radiation therapy
- peritoneal dialysis
- prognostic factors
- childhood cancer
- patient reported outcomes
- young adults