Unraveling the Complex Nexus of Human Papillomavirus (HPV) in Extragenital Keratinocyte Skin Tumors: A Comprehensive Analysis of Bowen's Disease and In Situ Squamous-Cell Carcinoma.

Conforti ClaudioChiara RetrosiMarina AgozzinoCaterina DianzaniErmanno NardonAnselmo OliveriEros AzzaliniStefania GuidaGiovanni PellacaniGiovanni Di LellaFranco RongiolettiIris ZalaudekSerena Bonin

Published in: Journal of clinical medicine (2024)

This comprehensive study delves into the intricate landscape surrounding the role of human papillomavirus (HPV) in extragenital keratinocyte skin tumors, specifically exploring Bowen's disease (BD) and in situ squamous-cell carcinoma (iSCC). Through a multifaceted examination, this research study elucidates the nuanced interplay of HPV, gender dynamics, anatomical site variations, and potential implications for the etiopathogenesis of these malignancies.

Keyphrases

squamous cell carcinoma
high grade
radiation therapy
lymph node metastasis
locally advanced
risk assessment
rectal cancer