LncRNA GATA3-AS1 facilitates tumour progression and immune escape in triple-negative breast cancer through destabilization of GATA3 but stabilization of PD-L1.

Ming ZhangNing WangPeng SongYingqiang FuYanlv RenZhigao LiJinsong Wang

Published in: Cell proliferation (2020)

GATA3-AS1 contributed to TNBC progression and immune evasion through stabilizing PD-L1 protein and degrading GATA3 protein, offering a new target for the treatment of TNBC.

Keyphrases

transcription factor
protein protein
amino acid
long non coding rna
small molecule
smoking cessation