Evidence of increased fecal granins in children with irritable bowel syndrome and correlates with symptoms.
Robert J ShulmanLena ÖhmanMats StridsbergKevin CainMagnus SimrénMargaret HeitkemperPublished in: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society (2018)
As measured by fecal granins, there is evidence of neuroimmune activation in children with IBS. Granins are related to abdominal pain symptoms, stooling frequency, and stool form in children with IBS. Sex influences the fecal concentration of CgB and SgIII.