Saliva as a sampling matrix for therapeutic drug monitoring of gentamicin in neonates: A prospective population pharmacokinetic and simulation study.
Amadou SambMatthijs D KruizingaYounes TallahiMichiel Joost van EsdonkWillemijn van HeelGertjan DriessenYuma BijleveldFrederik E StuurmanAdam A CohenAnton van KaamTimo R de HaanRon MathôtPublished in: British journal of clinical pharmacology (2021)
TDM of gentamicin using saliva is feasible and the difference in precision between saliva and plasma TDM may not be clinically relevant, especially for premature neonates.
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