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Indexes of aortic wave reflection are not augmented in estrogen-deficient physically active premenopausal women.

Emma O'DonnellJack M GoodmanJohn S FlorasPaula J Harvey
Published in: Scandinavian journal of medicine & science in sports (2020)
Despite hypoestrogenemia, functional compliance of the central arteries and central BP is not augmented, yet TPR is higher, in ExFHA versus ExOv. An acute bout of dynamic exercise did not alter AIx75 in ExFHA, suggesting blunted vascular responsiveness to exercise-induced increases in nitric oxide, possibly due to augmented vascular tone. These findings have relevance in understanding the vascular consequences of hypoestrogenemia during the premenopausal years.
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