Transcriptome signature of miRNA-26b KO mouse model suggests novel targets.

Emiel P.C. van der VorstMario A A PepeLinsey J F PetersMarkus HaberboschYvonne JansenRonald NaumannGeorgios T StathopoulosChristian WeberKiril Bidzhekov

Published in: BMC genomic data (2021)

miRNA-26b plays an important role in various pathologies, although causal relationships still have to be established. The described mouse model of miRNA-26b deficiency is a crucial first step towards the identification of the exact role of miRNA-26b in various diseases that could identify miRNA-26b as a promising novel diagnostic or even therapeutic target in a broad range of pathologies.

Keyphrases

mouse model
gene expression
genome wide
dna methylation
density functional theory
smoking cessation