CYLD deficiency causes auditory neuropathy due to reduced neurite outgrowth.

Song YangNan MaXuemei WuHua NiSiqi GaoLei SunPeng Zhounull TalaJie RanJun ZhouMin LiuDengwen Li

Published in: Journal of clinical laboratory analysis (2021)

The abnormal hearing of Cyld KO mice might be caused by a decrease in the length and number of neurites growing from auditory nerve cells in the cochlea, suggesting that CYLD is a key protein affecting hearing.

Keyphrases

hearing loss
induced apoptosis
working memory
cell cycle arrest
high fat diet induced
endoplasmic reticulum stress
protein protein
cell death
amino acid
signaling pathway
peripheral nerve
metabolic syndrome
skeletal muscle
binding protein
pi k akt
cell proliferation
wild type