Infiltrative vessel co-optive growth pattern induced by IQGAP3 overexpression promotes microvascular invasion in hepatocellular carcinoma.

Miaoling Tang Shuxia Zhang Meisongzhu Yang Rongni Feng Jinbin Lin Xiaohong Chen Yingru Xu Ruyuan Yu Xinyi Liao Ziwen Li Xincheng Li Man Li Qiliang Zhang Suwen Chen Wanying Qian Yuanji Liu Libing Song Jun Li

Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2024)

Our results revealed a plausible mechanism underlying IQGAP3-mediated microvascular invasion in HCC, and provided a potential target to develop therapeutic strategies to treat HCC with MVI.

Keyphrases

cell migration
cell proliferation
single cell
transcription factor
risk assessment
basal cell carcinoma